Pages: (67-92 )
Abstract
Multi-drug resistant bacteria are found in both hospital and community settings. There actions lead to limited
therapeutic choices. Acquisition of multidrug resistant pathogens may be due to various factors. The fight against
antimicrobial resistance can be won by synergy of the activities of all the relevant stakeholders.
Urine samples were obtained from patients attending two hospitals and Dam Community in Ogun State. Structured
questionnaire was also administered to all the participants. The urine samples were cultured and he pathogens
were identified. Antibiotic susceptibility testing was carried out on the pathogens to determine if they were multi-
drug resistant. The questionnaires were also analyzed to determine the predisposing factors to acquisition of MDR
pathogens among the participants.
The prevalence of MDR E. coli was highest in ODC 32 (42.7%). Most of the pathogens were multi-drug resistant.
predisposition to MDR pathogens is multi-factorial. The predisposition of MDR to Oyan Dam Community is their
total dependence on the dam which may be a reservoir for MDR pathogens.
ODC contains a larger percentage of individuals who harbour asymptomatic bacteriuria. This is due to the low
socio-economical status of this community whose means of likelihood is solely depedent on Oyan dam even to the
extent of using the water from the dam for domestic purposes including drinking. There is need to fight this public
health challenge by synergy of the activities of government agencies, communities, medical and pharmaceutical
industries etc.
Keywords: Multi-drug resistance, Oyan Dam, Antibiotics, Predisposing factors,